Safety
MemoHoney Side Effects and Drug Interactions
MemoHoney's amounts sit far below the doses that upset stomachs in research, so drug interactions matter more.
Mayo Clinic flags L-arginine alongside nitrates, sildenafil, diabetes drugs, anticoagulants and high blood pressure pills, and advises against it soon after a heart attack (Mayo Clinic, L-arginine).
Written by the MemoHoney editorial teamUpdated
Quick scan
What side effects can MemoHoney cause?
Research reports stomach upset, flushing and tingling for these ingredients, but at doses many times larger than one capsule.
| Label line | Per capsule | Research dose involved | What was reported |
|---|---|---|---|
| L-arginine, base and AKG | 200 mg + 200 mg | 9-30 g daily brought gut upset and a small blood pressure dip (NIH ODS, Exercise supplements) | Mayo also lists nausea, belly pain, bloating, gout, allergy and asthma flares (Mayo Clinic, L-arginine) |
| L-citrulline, HCl and malate | 100 mg + 100 mg | 8 g citrulline malate, given to 41 lifters | Six of them had an upset stomach (NIH ODS, Exercise supplements) |
| Beta-alanine | 40 mg | A single dose from 800 mg up | Pins and needles lasting 60-90 minutes, not harmful; some itching (NIH ODS, Exercise supplements) |
| Niacin | 7.5 mg NE | Nicotinic acid from roughly 30-50 mg | Red, warm skin known as flushing (NIH ODS, Niacin) |
| Calcium carbonate | 18 mg | No research dose; 1.5% of the Daily Value | None listed for this amount |
The tingle starts near 800 mg. One capsule holds 40 mg, so it would take 20 capsules at once to get there.
Ingredient by ingredient
Which MemoHoney ingredient carries the most risk?
L-arginine does. The risk comes from its effect on blood pressure and other drugs, not from common side effects.
L-arginine
Mayo Clinic advises against it soon after a heart attack, citing a possible higher death risk (Mayo Clinic, L-arginine). See the L-arginine page.
L-citrulline
Months-long safety is not well studied. Nonathletes had no adverse effects on up to 6 g daily over 4 weeks (NIH ODS, Exercise supplements).
Beta-alanine
Sport trials gave 1.6-6.4 g daily, for 8 weeks at most (NIH ODS, Exercise supplements). The capsule holds one-fortieth of the low end.
Niacin
The supplement ceiling is 35 mg a day (NIH ODS, Niacin). Add your multivitamin to the capsule's 7.5 mg. More on niacin.
Drug interactions
Which medicines interact with MemoHoney?
Seven drug groups clash with L-arginine, and two tuberculosis drugs affect niacin. The bottle names none of them.
| Medicine group | Common examples | Possible effect | Source |
|---|---|---|---|
| High blood pressure pills | Lisinopril, amlodipine, losartan | Readings fall below target | (Mayo Clinic, L-arginine) |
| Nitrate heart pills | Nitroglycerin, isosorbide | A steep fall in pressure | (Mayo Clinic, L-arginine) |
| Sildenafil | Used for erections or lung pressure | Pressure falls too far | (Mayo Clinic, L-arginine) |
| Anticoagulants, antiplatelets | Warfarin, clopidogrel, aspirin | Bleeding becomes more likely | (Mayo Clinic, L-arginine) |
| Diabetes medicines | Insulin, glipizide | Blood sugar may fall too low | (Mayo Clinic, L-arginine) |
| Potassium-sparing water pills | Spironolactone, amiloride, triamterene | Potassium may climb too high | (Mayo Clinic, L-arginine) |
| Isoproterenol | A hospital heart drug | Extra pressure drop | (Mayo Clinic, L-arginine) |
| Isoniazid, pyrazinamide | Tuberculosis treatment | Interferes with niacin | (NIH ODS, Niacin) |
The examples are common ones, not a full list. Pre-workout powders often add more arginine or citrulline, so count them too.
Before your first capsule
What should you bring to the pharmacist before taking MemoHoney?
The bottle and a full list of what you take. A pharmacist can check the whole list for clashes.
- The bottle, or a photo of the panel from the Supplement Facts page
- Every prescription, with its dose and time of day
- Pills you take only now and then, such as ED drugs or nitroglycerin
- Other supplements, especially multivitamins and pre-workout mixes
- Your history: heart attack, low blood pressure, asthma, gout, diabetes, pregnancy
Keep taking your prescribed medicine while you wait for answers. The capsule is what gets paused.
Know the signs
What do low blood pressure and low blood sugar feel like?
Both can follow an L-arginine interaction. These are general signs, not ones tied to MemoHoney.
Watch for
- Lightheadedness when you stand up
- Fainting or nearly fainting
- Blurred vision, nausea, unusual tiredness
Watch for
- Shakiness or sweating
- A pounding heartbeat, sudden hunger
- Irritability or confusion
Have a home cuff or glucose meter? Take a reading, write down the time, skip the capsule and call your doctor that day.
Stop rules
When should you stop taking MemoHoney?
At the first sign of allergy, fainting, low readings, or an asthma or gout flare. Then call your doctor.
Rash, hives or itching
Allergy is on Mayo Clinic's L-arginine list (Mayo Clinic, L-arginine). A swelling face or throat is an emergency.
Wheezing or a gout flare
L-arginine can inflame airways and is linked to gout.
Dizzy or shaky spells
Match them against the low pressure and low sugar signs above.
A new prescription
Pause until the pharmacist rechecks your list.
The label gives no taper, so stopping is simple. Note the date and the symptom for your doctor.

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Which symptoms mean call 911 right away?
Sudden stroke signs. Do not wait to see if they pass.
- Numbness or weakness of the face, arm or leg, mostly on one side
- Sudden confusion or trouble speaking
- Sudden trouble seeing or walking
- A sudden, severe headache with no known cause
Source: the CDC stroke list (CDC, Stroke signs). Note the time symptoms began.
On the bottle
What does the MemoHoney label warn about?
A general caution and a dose limit. It names groups of people, not medicines.

CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing.
Medicine questions are left to you. Timing is on the directions page.
Report it
Where can you report a reaction to MemoHoney?
Tell your doctor, then file a report with FDA MedWatch. The order desk can log it too.
File with FDA MedWatch
Anyone can report a supplement problem. Search "MedWatch" on fda.gov, or call 1-800-FDA-1088.
Keep the bottle
Note the lot code from the base. The batch page shows where it sits.
Call the order desk
Phone +1 (302) 200-3480 with your order ID to log the report or start a refund within 60 days of purchase.
Age and safety
Is MemoHoney safe for older adults?
Untested in older adults. The bigger issue at that age is how many medicines are already in use.
Heart, blood pressure and diabetes drugs are common later in life, and falls hurt more. If memory worry is the reason to buy, the memory health guide lists causes a doctor can treat.
FAQ
MemoHoney safety questions people search
Does MemoHoney cause headaches?
Headache is not among the L-arginine side effects Mayo Clinic lists (Mayo Clinic, L-arginine). A sudden, severe headache is different: call 911 (CDC, Stroke signs). If mild ones keep returning after you start, pause the capsule and tell your doctor.
Can I take MemoHoney with sildenafil or another ED pill?
Ask the prescriber first. Pairing L-arginine and sildenafil may lower blood pressure too far, per Mayo Clinic (Mayo Clinic, L-arginine). Other ED pills act in a similar way, so treat them the same.
Can you mix MemoHoney and warfarin or other blood thinners?
Get your doctor's OK before mixing them. Mayo Clinic links L-arginine plus anticoagulant or antiplatelet drugs with a higher bleeding risk (Mayo Clinic, L-arginine). Report easy bruising, nosebleeds or dark stools.
Can MemoHoney cause an allergic reaction?
It is possible. Mayo Clinic lists allergic reactions among L-arginine side effects (Mayo Clinic, L-arginine). Stop the capsule if a rash, hives or itching appears. Swelling of the face or throat, or trouble breathing, needs 911.
Does MemoHoney affect blood sugar?
It might if you use diabetes medicine, since Mayo Clinic says L-arginine can add to its sugar-lowering effect (Mayo Clinic, L-arginine). Check your readings more often in the first weeks.
What should I do if I feel dizzy after taking MemoHoney?
Sit or lie down until it passes. Check your blood pressure if you have a cuff, skip the next capsule and call your doctor, especially if you take heart or pressure pills (Mayo Clinic, L-arginine). Fainting, slurred speech or one-sided weakness means call 911 (CDC, Stroke signs).
Who wrote this
Written and reviewed by
Plain-language pages built from the label, the sales page and linked public health sources.
Page last updated . Read our editorial standards and how we check the reviews. This website is run by a U.S. shop that sells MemoHoney, not by the maker (the label says distributed by Instituto Experience, Ogden, UT). This site earns money when you buy through its order links.
Keep reading
More about MemoHoney

L-arginine
Two arginine lines, 400 mg in all: who can relax, who should ask a doctor, and which drugs clash.
Read more
L-arginine and heart medicines
Why the arginine in a memory capsule matters if you take heart or blood pressure medicine, and what to ask a pharmacist.
Read more
Who it's for
Four groups, from a reasonable fit to doctor first, plus a five-question check you can answer in a minute.
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